Here we study the beginning and propagation of the front evaporation and the transition to the critical heat flux (CHF) and the film boiling regime triggered by a steep, almost instantaneous increase in the release of heat from the heater is submerged lines Novec 7300 fluid.
Propagation path resulting evaporation front along the strip heater is measured and proven to increase exponentially in time, the difference from previous reports in the literature claiming that the increase only linearly. Because previous experiments employed a liquid such as water, coolant, acetone, ethanol, and alkali metals, which have a latent heat of relatively high evaporation and thus require a relatively high to be given, the burnout heater at the commencement of CHF and Film boil too quickly to allow longer observation time.
Thus, the earlier works was observed only a very short-time asymptotics propagation process, which means no time expansion of the exponential function, which is linear. On the other hand, in the experiment with Novec 7300 fluid, heater burnout delayed due to a much lower heat of latent vaporization, allowing for a longer observation of the propagation path, which seems to increase exponentially in time. The experiment begins with our theoretical predictions such behavior, and this theory is also described in this work. Due to the fact that this theory has been corroborated by experimental data, theoretical yield adequate explanation and description of CHF trigger and Film initial boiling.
This data set contains the experimental data local heat flux, the temperature of the walls and cancel the data profiles for vertical subcooled flow boiling of refrigerant Novec 649 in the copper wall. This article presents data on average boiling curve of one phase convection boiling movie fully developed during the six combinations of mass flux and subcooling.
profile is provided for void fraction Void, void detection frequency, the vacancy rate and the size of the void ligaments during three countries shared characteristics of each curve boiling. Thermocouples used to measure the heat flux and temperature. A single optical fiber and dual fiber micro probe used to obtain the data profiles void. Traverse mechanism is used to position the micro fiber optic probe relative to the surface of the heater.
Exponential vaporization fronts and critical heat flux in pool boiling.
Spray Evaluation and Methods Inoculation Point to the phenotype of Puccinia striiformis in wheat.
Fungus Puccinia striiformis cause yellow (stripe) rust in wheat worldwide. In this article, a new method utilizes fluid engineering (Novec 7100) as the carrier urediniospores compared with a commonly used method of inoculation. In general, Novec 7100 facilitated the application procedure faster and more flexible to spray inoculation and it gives very reproducible results for virulence phenotype. Six methods of inoculation point compared to find the most suitable for the assessment of pathogen aggressiveness.
Novec 7100 and the use of dry dilution with Lycopodium spores provide inoculation rate of 100% success in two independent experiments, which were significantly higher and more consistent than in Soltrol 170 spore suspension, water, water + Tween 20, and Noble that + Tween 20. Both Soltrol 170 and Novec 7100 enables precise quantification of inoculum, which is essential for quantitative assessment of epidemiological parameters.
Description: CRK, also known as p38, is a protein that in humans is encoded by the CRK gene. This gene is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It is mapped to 17p13.3. The protein participates in the Reelin signaling cascade downstream of DAB1. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of Crk functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
Description: This recombinant p38 antibody reacts to human p38 MAPK. It may also react to the rat and mouse protein, as predicted by immunogen homology.
Description: P38 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.
Description: P38 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is unconjugated.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is unconjugated.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to ATTO 390.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to ATTO 488.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to ATTO 565.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to ATTO 594.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to ATTO 633.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to ATTO 655.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to ATTO 680.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to ATTO 700.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to Alkaline Phosphatase.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to APC .
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to APC/Cy7.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to Biotin.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to Dylight 350.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to Dylight 405.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to Dylight 488.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to Dylight 594.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to Dylight 633.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to FITC.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to HRP.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to PE/ATTO 594.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to PerCP.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to RPE .
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is conjugated to Streptavidin.
Description: A polyclonal antibody for p38 from Human | Mouse | Rat | Bovine | Monkey | rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus). The antibody is produced in rabbit after immunization with Human A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100), IP (1:250). This p38 antibody is unconjugated.
MAPK P38 ELISA Kit| Mouse P38 Mitogen-activated Protein Kinase E
Description: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each.
Description: MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.
Description: MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.
Description: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. It has been implicated in various cancer pathologies and depending on the context, can facilitate or interfere with tumor development, and therefore has immense potential therapeutic interest.
Description: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. It has been implicated in various cancer pathologies and depending on the context, can facilitate or interfere with tumor development, and therefore has immense potential therapeutic interest.
Description: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. It has been implicated in various cancer pathologies and depending on the context, can facilitate or interfere with tumor development, and therefore has immense potential therapeutic interest.
Description: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. It has been implicated in various cancer pathologies and depending on the context, can facilitate or interfere with tumor development, and therefore has immense potential therapeutic interest.
Description: Mitogen-activated protein kinase 12 (MAP kinase 12), also known as p38 gamma, extracellular signal-regulated kinase 6 (ERK6) or stress-activated protein kinase 3 (SAPK3), is an enzyme that in humans is encoded by the MAPK12 gene. Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes.
new protocol to spray and inoculation point P. striiformis on wheat are presented, along with the prospects for applying this research and activity rust resistance breeding.
